A carregar...
Early Growth Response 1 (Egr-1) Is a Transcriptional Activator of β-Secretase 1 (BACE-1) in the Brain
Accumulation of amyloid-β peptide (Aβ) in the brain is regarded as central to Alzheimer's disease (AD) pathogenesis. Aβ is generated by a sequential cleavage of amyloid precursor protein (APP) by β-secretase 1 (BACE-1) followed by γ-secretase. BACE-1 cleavage of APP is the committed step in Aβ...
Na minha lista:
| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2016
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5064006/ https://ncbi.nlm.nih.gov/pubmed/27576688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.738849 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|