Early Growth Response 1 (Egr-1) Regulates N-Methyl-d-aspartate Receptor (NMDAR)-dependent Transcription of PSD-95 and α-Amino-3-hydroxy-5-methyl-4-isoxazole Propionic Acid Receptor (AMPAR) Trafficking in Hippocampal Primary Neurons

The N-methyl-d-aspartate receptor (NMDAR) controls synaptic plasticity and memory function and is one of the major inducers of transcription factor Egr-1 in the hippocampus. However, how Egr-1 mediates the NMDAR signal in neurons has remained unclear. Here, we show that the hippocampus of mice lacki...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Qin, Xike, Jiang, Yongjun, Tse, Yiu Chung, Wang, Yunling, Wong, Tak Pan, Paudel, Hemant K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2015
Schlagworte:
Neurobiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4705959/
https://ncbi.nlm.nih.gov/pubmed/26475861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.668889
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge