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Mouse genetic background contributes to hepatocyte susceptibility to Fas-mediated apoptosis

Liver disease progression is modulated by genetic modifiers in mouse strains and across human races and ethnicities. We hypothesized that hepatocyte culture duration and genetic background regulate hepatocyte susceptibility to apoptosis. Hepatocytes were isolated from FVB/N, C57BL/6, and C3H/He mice...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Biol Cell
Prif Awduron: Weerasinghe, Sujith V. W., Park, Min-Jung, Portney, Daniel A., Omary, M. Bishr
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society for Cell Biology 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063609/
https://ncbi.nlm.nih.gov/pubmed/27535425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-06-0423
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