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Amyloid β Is Not the Major Factor Accounting for Impaired Adult Hippocampal Neurogenesis in Mice Overexpressing Amyloid Precursor Protein

Adult hippocampal neurogenesis was impaired in several Alzheimer's disease models overexpressing mutant human amyloid precursor protein (hAPP). However, the effects of wild-type hAPP on adult neurogenesis and whether the impaired adult hippocampal neurogenesis was caused by amyloid β (Aβ) or AP...

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Bibliografiske detaljer
Udgivet i:Stem Cell Reports
Main Authors: Pan, Hongyu, Wang, Dongpi, Zhang, Xiaoqin, Zhou, Dongming, Zhang, Heng, Qian, Qi, He, Xiao, Liu, Zhaoling, Liu, Yunjin, Zheng, Tingting, Zhang, Ling, Wang, Mingkai, Sun, Binggui
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063569/
https://ncbi.nlm.nih.gov/pubmed/27693425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2016.08.019
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