Amyloid β Is Not the Major Factor Accounting for Impaired Adult Hippocampal Neurogenesis in Mice Overexpressing Amyloid Precursor Protein

Adult hippocampal neurogenesis was impaired in several Alzheimer's disease models overexpressing mutant human amyloid precursor protein (hAPP). However, the effects of wild-type hAPP on adult neurogenesis and whether the impaired adult hippocampal neurogenesis was caused by amyloid β (Aβ) or AP...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Pan, Hongyu, Wang, Dongpi, Zhang, Xiaoqin, Zhou, Dongming, Zhang, Heng, Qian, Qi, He, Xiao, Liu, Zhaoling, Liu, Yunjin, Zheng, Tingting, Zhang, Ling, Wang, Mingkai, Sun, Binggui
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063569/
https://ncbi.nlm.nih.gov/pubmed/27693425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2016.08.019
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