Immunoactivation induced by chronic viral infection inhibits viral replication and drives immunosuppression through sustained IFN‐I responses

Acute or chronic viral infections can lead to generalized immunosuppression. Several mechanisms, such as immunopathology of CD8(+) T cells, inhibitory receptors, or regulatory T (Treg) cells, contribute to immune dysfunction. Moreover, patients with chronic viral infections usually do not respond to...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Eur J Immunol
Prif Awduron: Honke, Nadine, Shaabani, Namir, Merches, Katja, Gassa, Asmae, Kraft, Anke, Ehrhardt, Katrin, Häussinger, Dieter, Löhning, Max, Dittmer, Ulf, Hengel, Hartmut, Recher, Mike, Lang, Philipp A., Lang, Karl S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2015
Pynciau:
Immunity to Infection
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063111/
https://ncbi.nlm.nih.gov/pubmed/26507703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201545765
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