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Metabolic shifts towards fatty acid usage and increased thermogenesis are associated with impaired adipogenesis in mice expressing human APOE4
BACKGROUND: The Apolipoprotein E (APOE) gene encodes for three isoforms in the human population (APOE2, APOE3, and APOE4). While the role of APOE in lipid metabolism is well characterized, the specific metabolic signatures of the APOE isoforms, during metabolic disorders, remain unclear. OBJECTIVE:...
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| Publicado no: | Int J Obes (Lond) |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5063049/ https://ncbi.nlm.nih.gov/pubmed/27163745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ijo.2016.93 |
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