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Apolipoprotein E knock-out and knock-in mice: atherosclerosis, metabolic syndrome, and beyond

Given the multiple differences between mice and men, it was once thought that mice could not be used to model atherosclerosis, principally a human disease. Apolipoprotein E-deficient (apoEKO) mice have convincingly changed this view, and the ability to model human-like plaques in these mice has prov...

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Detalhes bibliográficos
Main Authors: Pendse, Avani A., Arbones-Mainar, Jose M., Johnson, Lance A., Altenburg, Michael K., Maeda, Nobuyo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674752/
https://ncbi.nlm.nih.gov/pubmed/19060252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.R800070-JLR200
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