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Apolipoprotein E knock-out and knock-in mice: atherosclerosis, metabolic syndrome, and beyond
Given the multiple differences between mice and men, it was once thought that mice could not be used to model atherosclerosis, principally a human disease. Apolipoprotein E-deficient (apoEKO) mice have convincingly changed this view, and the ability to model human-like plaques in these mice has prov...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2674752/ https://ncbi.nlm.nih.gov/pubmed/19060252 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.R800070-JLR200 |
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