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Impaired adipogenic response to thiazolidinediones in mice expressing human apolipoproteinE4
Thiazolidinediones (TZDs) are insulin sensitizers used to treat patients with insulin resistance. To assess potential gene-drug interactions, mice expressing human apolipoprotein E3 or E4 (APOE3 or APOE4) were fed a Western-type high-fat diet for 12 wk, at which time they developed similarly impaire...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Federation of American Societies for Experimental Biology
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2996914/ https://ncbi.nlm.nih.gov/pubmed/20501792 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-159517 |
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