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Impaired adipogenic response to thiazolidinediones in mice expressing human apolipoproteinE4

Thiazolidinediones (TZDs) are insulin sensitizers used to treat patients with insulin resistance. To assess potential gene-drug interactions, mice expressing human apolipoprotein E3 or E4 (APOE3 or APOE4) were fed a Western-type high-fat diet for 12 wk, at which time they developed similarly impaire...

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Auteurs principaux: Arbones-Mainar, Jose M., Johnson, Lance A., Altenburg, Michael K., Kim, Hyung-Suk, Maeda, Nobuyo
Format: Artigo
Langue:Inglês
Publié: Federation of American Societies for Experimental Biology 2010
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996914/
https://ncbi.nlm.nih.gov/pubmed/20501792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-159517
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