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Multiple consecutive initiation of replication producing novel brush-like intermediates at the termini of linear viral dsDNA genomes with hairpin ends

Linear dsDNA replicons with hairpin ends are found in the three domains of life, mainly associated with plasmids and viruses including the poxviruses, some phages and archaeal rudiviruses. However, their replication mechanism is not clearly understood. In this study, we find that the rudivirus SIRV2...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Martínez-Alvarez, Laura, Bell, Stephen D., Peng, Xu
Format: Artigo
Language:Inglês
Published: Oxford University Press 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5062984/
https://ncbi.nlm.nih.gov/pubmed/27407114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw636
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