The role of sequence context, nucleotide pool balance and stress in 2′-deoxynucleotide misincorporation in viral, bacterial and mammalian RNA

The misincorporation of 2′-deoxyribonucleotides (dNs) into RNA has important implications for the function of non-coding RNAs, the translational fidelity of coding RNAs and the mutagenic evolution of viral RNA genomes. However, quantitative appreciation for the degree to which dN misincorporation oc...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Wang, Jin, Dong, Hongping, Chionh, Yok Hian, McBee, Megan E., Sirirungruang, Sasilada, Cunningham, Richard P., Shi, Pei-Yong, Dedon, Peter C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5062971/
https://ncbi.nlm.nih.gov/pubmed/27365049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw572
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