The deoxynucleotide triphosphohydrolase SAMHD1 is a major regulator of DNA precursor pools in mammalian cells

Sterile alpha motif and HD-domain containing protein 1 (SAMHD1) is a triphosphohydrolase converting deoxynucleoside triphosphates (dNTPs) to deoxynucleosides. The enzyme was recently identified as a component of the human innate immune system that restricts HIV-1 infection by removing dNTPs required...

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Detaylı Bibliyografya
Asıl Yazarlar: Franzolin, Elisa, Pontarin, Giovanna, Rampazzo, Chiara, Miazzi, Cristina, Ferraro, Paola, Palumbo, Elisa, Reichard, Peter, Bianchi, Vera
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2013
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3761606/
https://ncbi.nlm.nih.gov/pubmed/23858451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1312033110
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