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Drosophila clueless is involved in Parkin-dependent mitophagy by promoting VCP-mediated Marf degradation

PINK1/Parkin-mediated mitochondrial quality control (MQC) requires valosin-containing protein (VCP)-dependent Mitofusin/Marf degradation to prevent damaged organelles from fusing with the healthy mitochondrial pool, facilitating mitochondrial clearance by autophagy. Drosophila clueless (clu) was fou...

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Bibliografiska uppgifter
I publikationen:Hum Mol Genet
Huvudupphovsmän: Wang, Zong-Heng, Clark, Cheryl, Geisbrecht, Erika R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2016
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5062585/
https://ncbi.nlm.nih.gov/pubmed/26931463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw067
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