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Drosophila clueless is involved in Parkin-dependent mitophagy by promoting VCP-mediated Marf degradation
PINK1/Parkin-mediated mitochondrial quality control (MQC) requires valosin-containing protein (VCP)-dependent Mitofusin/Marf degradation to prevent damaged organelles from fusing with the healthy mitochondrial pool, facilitating mitochondrial clearance by autophagy. Drosophila clueless (clu) was fou...
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| Udgivet i: | Hum Mol Genet |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5062585/ https://ncbi.nlm.nih.gov/pubmed/26931463 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw067 |
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