EpCAM-dependent extracellular vesicles from intestinal epithelial cells maintain intestinal tract immune balance

How the intestinal tract develops a tolerance to foreign antigens is still largely unknown. Here we report that extracellular vesicles (EVs) with TGF-β1-dependent immunosuppressive activity are produced by intestinal epithelial cells (IECs) under physiological conditions. Transfer of these EVs into...

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Publicado en:Nat Commun
Autores principales: Jiang, Lingling, Shen, Yingying, Guo, Danfeng, Yang, Diya, Liu, Jiajun, Fei, Xuefeng, Yang, Yunshan, Zhang, Buyi, Lin, Zhendong, Yang, Fei, Wang, Xiaojian, Wang, Keyi, Wang, Jianli, Cai, Zhijian
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5062543/
https://ncbi.nlm.nih.gov/pubmed/27721471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13045
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