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Tissue-specific and convergent metabolic transformation of cancer correlates with metastatic potential and patient survival

Cancer cells undergo a multifaceted rewiring of cellular metabolism to support their biosynthetic needs. Although the major determinants of this metabolic transformation have been elucidated, their broad biological implications and clinical relevance are unclear. Here we systematically analyse the e...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Gaude, Edoardo, Frezza, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5062467/
https://ncbi.nlm.nih.gov/pubmed/27721378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13041
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