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Tissue-specific and convergent metabolic transformation of cancer correlates with metastatic potential and patient survival

Cancer cells undergo a multifaceted rewiring of cellular metabolism to support their biosynthetic needs. Although the major determinants of this metabolic transformation have been elucidated, their broad biological implications and clinical relevance are unclear. Here we systematically analyse the e...

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Pubblicato in:Nat Commun
Autori principali: Gaude, Edoardo, Frezza, Christian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5062467/
https://ncbi.nlm.nih.gov/pubmed/27721378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13041
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