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The contribution of major histocompatibility complex contacts to the affinity and kinetics of T cell receptor binding
The interaction between the T cell antigen receptor (TCR) and antigenic peptide in complex with major histocompatibility complex (MHC) molecules is a crucial step in T cell activation. The relative contributions of TCR:peptide and TCR:MHC contacts to the overall binding energy remain unclear. This h...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5062128/ https://ncbi.nlm.nih.gov/pubmed/27734930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35326 |
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