Kinetics and Mechanics of Two-Dimensional Interactions between T Cell Receptors and Different Activating Ligands

Adaptive immune responses are driven by interactions between T cell antigen receptors (TCRs) and complexes of peptide antigens (p) bound to Major Histocompatibility Complex proteins (MHC) on the surface of antigen-presenting cells. Many experiments support the hypothesis that T cell response is quan...

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Bibliographic Details
Main Authors: Robert, Philippe, Aleksic, Milos, Dushek, Omer, Cerundolo, Vincenzo, Bongrand, Pierre, van der Merwe, P. Anton
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2012
Subjects:
Cellular Biophysics and Electrophysiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260781/
https://ncbi.nlm.nih.gov/pubmed/22339861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.11.4018
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