Effects of aged garlic extract and FruArg on gene expression and signaling pathways in lipopolysaccharide-activated microglial cells

Aged garlic extract (AGE) is widely used as a dietary supplement on account of its protective effects against oxidative stress and inflammation. But less is known about specific molecular targets of AGE and its bioactive components, including N-α-(1-deoxy-D-fructos-1-yl)-L-arginine (FruArg). Our rec...

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Vydáno v:Sci Rep
Hlavní autoři: Song, Hailong, Lu, Yuan, Qu, Zhe, Mossine, Valeri V., Martin, Matthew B., Hou, Jie, Cui, Jiankun, Peculis, Brenda A., Mawhinney, Thomas P., Cheng, Jianlin, Greenlief, C. Michael, Fritsche, Kevin, Schmidt, Francis J., Walter, Ronald B., Lubahn, Dennis B., Sun, Grace Y., Gu, Zezong
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5062119/
https://ncbi.nlm.nih.gov/pubmed/27734935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35323
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