Effects of aged garlic extract and FruArg on gene expression and signaling pathways in lipopolysaccharide-activated microglial cells

Aged garlic extract (AGE) is widely used as a dietary supplement on account of its protective effects against oxidative stress and inflammation. But less is known about specific molecular targets of AGE and its bioactive components, including N-α-(1-deoxy-D-fructos-1-yl)-L-arginine (FruArg). Our rec...

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Publicado no:Sci Rep
Main Authors: Song, Hailong, Lu, Yuan, Qu, Zhe, Mossine, Valeri V., Martin, Matthew B., Hou, Jie, Cui, Jiankun, Peculis, Brenda A., Mawhinney, Thomas P., Cheng, Jianlin, Greenlief, C. Michael, Fritsche, Kevin, Schmidt, Francis J., Walter, Ronald B., Lubahn, Dennis B., Sun, Grace Y., Gu, Zezong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5062119/
https://ncbi.nlm.nih.gov/pubmed/27734935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35323
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