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TP53 copy number expansion is associated with the evolution of increased body size and an enhanced DNA damage response in elephants

A major constraint on the evolution of large body sizes in animals is an increased risk of developing cancer. There is no correlation, however, between body size and cancer risk. This lack of correlation is often referred to as 'Peto's Paradox'. Here, we show that the elephant genome...

詳細記述

保存先:
書誌詳細
出版年:eLife
主要な著者: Sulak, Michael, Fong, Lindsey, Mika, Katelyn, Chigurupati, Sravanthi, Yon, Lisa, Mongan, Nigel P, Emes, Richard D, Lynch, Vincent J
フォーマット: Artigo
言語:Inglês
出版事項: eLife Sciences Publications, Ltd 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5061548/
https://ncbi.nlm.nih.gov/pubmed/27642012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.11994
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