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MYC, FBXW7 and TP53 copy number variation and expression in Gastric Cancer
BACKGROUND: MYC deregulation is a common event in gastric carcinogenesis, usually as a consequence of gene amplification, chromosomal translocations, or posttranslational mechanisms. FBXW7 is a p53-controlled tumor-suppressor that plays a role in the regulation of cell cycle exit and reentry via MYC...
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Main Authors: | , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3851138/ https://ncbi.nlm.nih.gov/pubmed/24053468 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-13-141 |
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