MYC, FBXW7 and TP53 copy number variation and expression in Gastric Cancer

BACKGROUND: MYC deregulation is a common event in gastric carcinogenesis, usually as a consequence of gene amplification, chromosomal translocations, or posttranslational mechanisms. FBXW7 is a p53-controlled tumor-suppressor that plays a role in the regulation of cell cycle exit and reentry via MYC...

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Main Authors: Calcagno, Danielle Queiroz, Freitas, Vanessa Morais, Leal, Mariana Ferreira, de Souza, Carolina Rosal Teixeira, Demachki, Samia, Montenegro, Raquel, Assumpção, Paulo Pimentel, Khayat, André Salim, Smith, Marília de Arruda Cardoso, dos Santos, Andrea Kely Campos Ribeiro, Burbano, Rommel Rodriguez
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3851138/
https://ncbi.nlm.nih.gov/pubmed/24053468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-13-141
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