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Targeting DNA Mismatches with Rhodium Metalloinsertors
DNA has been exploited as a biological target of chemotherapeutics since the 1940s. Traditional chemotherapeutics, such as cisplatin and DNA-alkylating agents, rely primarily on increased uptake by rapidly proliferating cancer cells for therapeutic effects, but this strategy can result in off-target...
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| 發表在: | Inorganica Chim Acta |
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| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5061454/ https://ncbi.nlm.nih.gov/pubmed/27746507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ica.2016.01.021 |
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