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A Family of Rhodium Complexes with Selective Toxicity towards Mismatch Repair-Deficient Cancers
Rhodium metalloinsertors are a unique set of metal complexes that bind specifically to DNA base pair mismatches in vitro and kill mismatch repair (MMR)-deficient cells at lower concentrations than their MMR-proficient counterparts. A family of metalloinsertors containing rhodium-oxygen ligand coordi...
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| Publicado no: | J Am Chem Soc |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5965675/ https://ncbi.nlm.nih.gov/pubmed/29620877 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b02271 |
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