Characterization of the tumor suppressor protein p53 as a protein kinase C substrate and a S100b-binding protein.
We report here that the negative cell cycle regulator protein p53 is an in vivo and in vitro substrate for protein kinase C, a cellular receptor for the tumor-promoter phorbol esters. We also demonstrate that p53 interacts in a calcium-dependent manner with S100b, a member of the S100 protein family...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1992
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50606/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1454855/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.23.11627 |
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