Characterization of the tumor suppressor protein p53 as a protein kinase C substrate and a S100b-binding protein.

We report here that the negative cell cycle regulator protein p53 is an in vivo and in vitro substrate for protein kinase C, a cellular receptor for the tumor-promoter phorbol esters. We also demonstrate that p53 interacts in a calcium-dependent manner with S100b, a member of the S100 protein family...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Baudier, J, Delphin, C, Grunwald, D, Khochbin, S, Lawrence, J J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50606/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1454855/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.23.11627
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