miRNA-558 promotes gastric cancer progression through attenuating Smad4-mediated repression of heparanase expression

Previous studies have indicated that as the only mammalian endo-β-D-glucuronidase, heparanase (HPSE) is up-regulated and associated with poor prognosis in gastric cancer, while the underlying mechanisms still remain to be determined. Herein, through integrative analysis of public datasets, we found...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Death Dis
Prif Awduron: Zheng, Liduan, Jiao, Wanju, Song, Huajie, Qu, Hongxia, Li, Dan, Mei, Hong, Chen, Yajun, Yang, Feng, Li, Huanhuan, Huang, Kai, Tong, Qiangsong
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2016
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5059886/
https://ncbi.nlm.nih.gov/pubmed/27685626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.293
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