miRNA-558 promotes gastric cancer progression through attenuating Smad4-mediated repression of heparanase expression

Previous studies have indicated that as the only mammalian endo-β-D-glucuronidase, heparanase (HPSE) is up-regulated and associated with poor prognosis in gastric cancer, while the underlying mechanisms still remain to be determined. Herein, through integrative analysis of public datasets, we found...

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Vydáno v:Cell Death Dis
Hlavní autoři: Zheng, Liduan, Jiao, Wanju, Song, Huajie, Qu, Hongxia, Li, Dan, Mei, Hong, Chen, Yajun, Yang, Feng, Li, Huanhuan, Huang, Kai, Tong, Qiangsong
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5059886/
https://ncbi.nlm.nih.gov/pubmed/27685626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.293
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