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Smad4 suppresses the tumorigenesis and aggressiveness of neuroblastoma through repressing the expression of heparanase
Heparanase (HPSE) is the only endo-β-D-glucuronidase that is correlated with the progression of neuroblastoma (NB), the most common extracranial malignancy in childhood. However, the mechanisms underlying HPSE expression in NB still remain largely unknown. Herein, through analyzing cis-regulatory el...
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| Udgivet i: | Sci Rep |
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| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5011643/ https://ncbi.nlm.nih.gov/pubmed/27595937 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32628 |
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