Smad4 suppresses the tumorigenesis and aggressiveness of neuroblastoma through repressing the expression of heparanase

Heparanase (HPSE) is the only endo-β-D-glucuronidase that is correlated with the progression of neuroblastoma (NB), the most common extracranial malignancy in childhood. However, the mechanisms underlying HPSE expression in NB still remain largely unknown. Herein, through analyzing cis-regulatory el...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Qu, Hongxia, Zheng, Liduan, Jiao, Wanju, Mei, Hong, Li, Dan, Song, Huajie, Fang, Erhu, Wang, Xiaojing, Li, Shiwang, Huang, Kai, Tong, Qiangsong
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5011643/
https://ncbi.nlm.nih.gov/pubmed/27595937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32628
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