A distinct holoenzyme organization for two-subunit pyruvate carboxylase

Pyruvate carboxylase (PC) has important roles in metabolism and is crucial for virulence for some pathogenic bacteria. PC contains biotin carboxylase (BC), carboxyltransferase (CT) and biotin carboxyl carrier protein (BCCP) components. It is a single-chain enzyme in eukaryotes and most bacteria, and...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Choi, Philip H., Jo, Jeanyoung, Lin, Yu-Cheng, Lin, Min-Han, Chou, Chi-Yuan, Dietrich, Lars E. P., Tong, Liang
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5059739/
https://ncbi.nlm.nih.gov/pubmed/27708276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12713
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