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Characterizing the importance of the biotin carboxylase domain dimer for S. aureus pyruvate carboxylase catalysis
Biotin carboxylase (BC) is a conserved component among biotin-dependent carboxylases and catalyzes the MgATP-dependent carboxylation of biotin, using bicarbonate as the CO(2) donor. Studies with E. coli BC have suggested long-range communication between the two active sites of a dimer, although its...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3553216/ https://ncbi.nlm.nih.gov/pubmed/23286247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi301294d |
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