Novel Insights into the Biotin Carboxylase Domain Reactions of Pyruvate Carboxylase from Rhizobium etli

The catalytic mechanism of the MgATP-dependent carboxylation of biotin in the biotin carboxylase domain of pyruvate carboxylase from R. etli (RePC) is common to the biotin-dependent carboxylases. The current site-directed mutagenesis study has clarified the catalytic functions of several residues pr...

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Hauptverfasser: Zeczycki, Tonya N., Menefee, Ann L., Adina-Zada, Abdussalam, Jitrapakdee, Sarawut, Surinya, Kathy H., Wallace, John C., Attwood, Paul V., St. Maurice, Martin, Cleland, W. Wallace
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3211089/
https://ncbi.nlm.nih.gov/pubmed/21957995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi2012788
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