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Activation and inhibition of pyruvate carboxylase from Rhizobium etli()

While crystallographic structures of the R. etli pyruvate carboxylase (PC) holoenzyme revealed the location and probable positioning of the essential activator, Mg(2+), and non-essential activator, acetyl-CoA, an understanding of how they affect catalysis remains unclear. The current steady-state ki...

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Detalhes bibliográficos
Main Authors: Zeczycki, Tonya N., Menefee, Ann L., Jitrapakdee, Sarawut, Wallace, John C., Attwood, Paul V., Maurice, Martin St., Cleland, W. Wallace
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210919/
https://ncbi.nlm.nih.gov/pubmed/21958066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi201276r
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