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Regulation of actin catch-slip bonds with a RhoA-formin module

The dynamic turnover of the actin cytoskeleton is regulated cooperatively by force and biochemical signaling. We previously demonstrated that actin depolymerization under force is governed by catch-slip bonds mediated by force-induced K113:E195 salt-bridges. Yet, the biochemical regulation as well a...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lee, Cho-yin, Lou, Jizhong, Wen, Kuo-Kuang, McKane, Melissa, Eskin, Suzanne G., Rubenstein, Peter A., Chien, Shu, Ono, Shoichiro, Zhu, Cheng, McIntire, Larry V.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5059732/
https://ncbi.nlm.nih.gov/pubmed/27731359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35058
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