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Actin depolymerization under force is governed by lysine 113:glutamic acid 195-mediated catch-slip bonds
As a key element in the cytoskeleton, actin filaments are highly dynamic structures that constantly sustain forces. However, the fundamental question of how force regulates actin dynamics is unclear. Using atomic force microscopy force-clamp experiments, we show that tensile force regulates G-actin/...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3612643/ https://ncbi.nlm.nih.gov/pubmed/23460697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1218407110 |
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