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Actin depolymerization under force is governed by lysine 113:glutamic acid 195-mediated catch-slip bonds

As a key element in the cytoskeleton, actin filaments are highly dynamic structures that constantly sustain forces. However, the fundamental question of how force regulates actin dynamics is unclear. Using atomic force microscopy force-clamp experiments, we show that tensile force regulates G-actin/...

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מידע ביבליוגרפי
Main Authors: Lee, Cho-yin, Lou, Jizhong, Wen, Kuo-kuang, McKane, Melissa, Eskin, Suzanne G., Ono, Shoichiro, Chien, Shu, Rubenstein, Peter A., Zhu, Cheng, McIntire, Larry V.
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612643/
https://ncbi.nlm.nih.gov/pubmed/23460697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1218407110
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