Inhibition of cancer cell epithelial mesenchymal transition by normal fibroblasts via production of 5-methoxytryptophan

We reported previously that human fibroblasts release 5-methoxytryptophan (5-MTP) which inhibits cancer cell COX-2 overexpression and suppresses cancer cell migration and metastasis. To determine whether fibroblasts block cancer cell epithelial mesenchymal transition (EMT) via 5-MTP, we evaluated th...

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Udgivet i:Oncotarget
Main Authors: Cheng, Huei-Hsuan, Chu, Ling-Yun, Chiang, Li-Yi, Chen, Hua-Ling, Kuo, Cheng-Chin, Wu, Kenneth K.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5058753/
https://ncbi.nlm.nih.gov/pubmed/27145282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9111
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