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Endothelium-Derived 5-Methoxytryptophan Protects Endothelial Barrier Function by Blocking p38 MAPK Activation

The endothelial junction is tightly controlled to restrict the passage of blood cells and solutes. Disruption of endothelial barrier function by bacterial endotoxins, cytokines or growth factors results in inflammation and vascular damage leading to vascular diseases. We have identified 5-methoxytry...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Chu, Ling-Yun, Wang, Yi-Fu, Cheng, Huei-Hsuan, Kuo, Cheng-Chin, Wu, Kenneth K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4803234/
https://ncbi.nlm.nih.gov/pubmed/27002329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152166
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