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Endothelium-Derived 5-Methoxytryptophan Protects Endothelial Barrier Function by Blocking p38 MAPK Activation

The endothelial junction is tightly controlled to restrict the passage of blood cells and solutes. Disruption of endothelial barrier function by bacterial endotoxins, cytokines or growth factors results in inflammation and vascular damage leading to vascular diseases. We have identified 5-methoxytry...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Chu, Ling-Yun, Wang, Yi-Fu, Cheng, Huei-Hsuan, Kuo, Cheng-Chin, Wu, Kenneth K.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4803234/
https://ncbi.nlm.nih.gov/pubmed/27002329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152166
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