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Characterizing runs of homozygosity and their impact on risk for psychosis in a population isolate

An increased abundance of runs of homozygosity (ROH) has been associated with risk for various diseases, including schizophrenia. Here we investigate the characteristics of ROH in Palau, an Oceanic population, evaluating whether these characteristics are related to risk for psychotic disorders and t...

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Publicat a:Am J Med Genet B Neuropsychiatr Genet
Autors principals: Melhem, Nadine M., Lu, Cong, Dresbold, Cara, Middleton, Frank A., Klei, Lambertus, Wood, Shawn, Faraone, Stephen V, Vinogradov, Sophia, Tiobech, Josepha, Yano, Victor, Roeder, Kathryn, Byerley, William, Myles-Worsley, Marina, Devlin, Bernie
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5058445/
https://ncbi.nlm.nih.gov/pubmed/24980794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.b.32255
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