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Characterizing runs of homozygosity and their impact on risk for psychosis in a population isolate

An increased abundance of runs of homozygosity (ROH) has been associated with risk for various diseases, including schizophrenia. Here we investigate the characteristics of ROH in Palau, an Oceanic population, evaluating whether these characteristics are related to risk for psychotic disorders and t...

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Detalhes bibliográficos
Publicado no:Am J Med Genet B Neuropsychiatr Genet
Main Authors: Melhem, Nadine M., Lu, Cong, Dresbold, Cara, Middleton, Frank A., Klei, Lambertus, Wood, Shawn, Faraone, Stephen V, Vinogradov, Sophia, Tiobech, Josepha, Yano, Victor, Roeder, Kathryn, Byerley, William, Myles-Worsley, Marina, Devlin, Bernie
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5058445/
https://ncbi.nlm.nih.gov/pubmed/24980794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.b.32255
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