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Characterizing runs of homozygosity and their impact on risk for psychosis in a population isolate

An increased abundance of runs of homozygosity (ROH) has been associated with risk for various diseases, including schizophrenia. Here we investigate the characteristics of ROH in Palau, an Oceanic population, evaluating whether these characteristics are related to risk for psychotic disorders and t...

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Veröffentlicht in:Am J Med Genet B Neuropsychiatr Genet
Hauptverfasser: Melhem, Nadine M., Lu, Cong, Dresbold, Cara, Middleton, Frank A., Klei, Lambertus, Wood, Shawn, Faraone, Stephen V, Vinogradov, Sophia, Tiobech, Josepha, Yano, Victor, Roeder, Kathryn, Byerley, William, Myles-Worsley, Marina, Devlin, Bernie
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5058445/
https://ncbi.nlm.nih.gov/pubmed/24980794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.b.32255
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