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Runs of Homozygosity, Copy Number Variation, and Risk for Depression and Suicidal Behavior in an Arab Bedouin Kindred

OBJECTIVES: Inbreeding increases the probability of homozygosity of deleterious alleles. Inbreeding and Runs of homozygosity (ROH) are associated with increased risk for disease phentoypes, including schizophrenia and other psychiatric disorders. Effects of inbreeding, ROH, homozygous deletions, and...

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Detalhes bibliográficos
Publicado no:Psychiatr Genet
Main Authors: Melhem, Nadine M., Hamdan, Sami, Klei, Lambertus, Wood, Shawn, Zelazny, Jamie, Frisch, Amos, Weizman, Abraham, Carmel, Miri, Michaelovsky, Elena, Farbstein, Ilana, Wasserman, Danuta, el Heib, Muhammad, Ferrell, Robert, Apter, Alan, Devlin, Bernie, Brent, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5572483/
https://ncbi.nlm.nih.gov/pubmed/28570395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/YPG.0000000000000177
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