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Targeting of the epidermal growth factor receptor with mesoporphyrin IX-peptide conjugates
The synthesis and in vitro evaluation of four mesoporphyrin IX-peptide conjugates designed to target EGFR, over-expressed in colorectal and other cancers, are reported. Two peptides with known affinity for EGFR, LARLLT (1) and GYHWYGYTPQNVI (2), were conjugated to mesoporphyrin IX (MPIX, 3) via one...
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| Udgivet i: | J Porphyr Phthalocyanines |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5058426/ https://ncbi.nlm.nih.gov/pubmed/27738394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1142/S1088424616500115 |
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