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Click Conjugation of Boron Dipyrromethene (BODIPY) Fluorophores to EGFR-Targeting Linear and Cyclic Peptides

Through a simple 1,3-cycloaddition reaction, three BODIPY-peptide conjugates that target the extracellular domain of the epidermal growth factor receptor (EGFR) were prepared and their ability for binding to EGFR was investigated. The peptide ligands K(N(3))LARLLT and its cyclic analog cyclo(K(N(3))...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Williams, Tyrslai M., Kaufman, Nichole E. M., Zhou, Zehua, Singh, Sitanshu S., Jois, Seetharama D., Vicente, Maria da Graça H.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7865655/
https://ncbi.nlm.nih.gov/pubmed/33498632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26030593
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