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Click Conjugation of Boron Dipyrromethene (BODIPY) Fluorophores to EGFR-Targeting Linear and Cyclic Peptides

Through a simple 1,3-cycloaddition reaction, three BODIPY-peptide conjugates that target the extracellular domain of the epidermal growth factor receptor (EGFR) were prepared and their ability for binding to EGFR was investigated. The peptide ligands K(N(3))LARLLT and its cyclic analog cyclo(K(N(3))...

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Pubblicato in:Molecules
Autori principali: Williams, Tyrslai M., Kaufman, Nichole E. M., Zhou, Zehua, Singh, Sitanshu S., Jois, Seetharama D., Vicente, Maria da Graça H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7865655/
https://ncbi.nlm.nih.gov/pubmed/33498632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26030593
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