Click Conjugation of Boron Dipyrromethene (BODIPY) Fluorophores to EGFR-Targeting Linear and Cyclic Peptides

Through a simple 1,3-cycloaddition reaction, three BODIPY-peptide conjugates that target the extracellular domain of the epidermal growth factor receptor (EGFR) were prepared and their ability for binding to EGFR was investigated. The peptide ligands K(N(3))LARLLT and its cyclic analog cyclo(K(N(3))...

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Veröffentlicht in:Molecules
Hauptverfasser: Williams, Tyrslai M., Kaufman, Nichole E. M., Zhou, Zehua, Singh, Sitanshu S., Jois, Seetharama D., Vicente, Maria da Graça H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7865655/
https://ncbi.nlm.nih.gov/pubmed/33498632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26030593
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