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Neutrophil mechanotransduction: A GEF to sense fluid shear stress

Forces deriving from blood flow shear modulate vascular adherence and transendothelial migration of leukocytes into inflamed tissues, but the mechanisms by which shear is sensed are unclear. In this issue, Fine et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201603109) identify the guanosi...

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Publicat a:J Cell Biol
Autor principal: Niethammer, Philipp
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5057290/
https://ncbi.nlm.nih.gov/pubmed/27738002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201609101
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