Defective fluid shear stress mechanotransduction mediates hereditary hemorrhagic telangiectasia

Morphogenesis of the vascular system is strongly modulated by mechanical forces from blood flow. Hereditary hemorrhagic telangiectasia (HHT) is an inherited autosomal-dominant disease in which arteriovenous malformations and telangiectasias accumulate with age. Most cases are linked to heterozygous...

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Bibliografiske detaljer
Udgivet i:J Cell Biol
Main Authors: Baeyens, Nicolas, Larrivée, Bruno, Ola, Roxana, Hayward-Piatkowskyi, Brielle, Dubrac, Alexandre, Huang, Billy, Ross, Tyler D., Coon, Brian G., Min, Elizabeth, Tsarfati, Maya, Tong, Haibin, Eichmann, Anne, Schwartz, Martin A.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2016
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Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5037412/
https://ncbi.nlm.nih.gov/pubmed/27646277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201603106
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