Defective fluid shear stress mechanotransduction mediates hereditary hemorrhagic telangiectasia

Morphogenesis of the vascular system is strongly modulated by mechanical forces from blood flow. Hereditary hemorrhagic telangiectasia (HHT) is an inherited autosomal-dominant disease in which arteriovenous malformations and telangiectasias accumulate with age. Most cases are linked to heterozygous...

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Bibliographic Details
Published in:J Cell Biol
Main Authors: Baeyens, Nicolas, Larrivée, Bruno, Ola, Roxana, Hayward-Piatkowskyi, Brielle, Dubrac, Alexandre, Huang, Billy, Ross, Tyler D., Coon, Brian G., Min, Elizabeth, Tsarfati, Maya, Tong, Haibin, Eichmann, Anne, Schwartz, Martin A.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2016
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5037412/
https://ncbi.nlm.nih.gov/pubmed/27646277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201603106
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