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Reprogramming the Dynamin 2 mRNA by Spliceosome-mediated RNA Trans-splicing

Dynamin 2 (DNM2) is a large GTPase, ubiquitously expressed, involved in membrane trafficking and regulation of actin and microtubule cytoskeletons. DNM2 mutations cause autosomal dominant centronuclear myopathy which is a rare congenital myopathy characterized by skeletal muscle weakness and histopa...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Trochet, Delphine, Prudhon, Bernard, Jollet, Arnaud, Lorain, Stéphanie, Bitoun, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5056991/
https://ncbi.nlm.nih.gov/pubmed/27623444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2016.67
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